10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

Baking soda for acid reflux: Effectiveness, risks, and side effects

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

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Acid reflux is a burning sensation in the chest that some people experience after eating. Baking soda may help relieve symptoms, but people should use it with care.

Acid reflux, also known as heartburn, occurs when stomach acid backs up into the food pipe, causing discomfort. Some people may experience a sour taste in their mouth.

According to the American College of Gastroenterology, over 60 million Americans experience acid reflux at least once a month. Some studies suggest over 15 million have it daily.

Anyone who experiences acid reflux more than twice a week should seek medical treatment, as it may be a sign of gastroesophageal reflux disease (GERD) or another underlying condition.

However, if acid reflux comes and goes and lasts less than 2 weeks, baking soda, or sodium bicarbonate may help.

Some over-the-counter (OTC) and prescription drugs for acid reflux contain sodium bicarbonate. For example, Zegerid combines sodium bicarbonate with omeprazole.

However, some people also use baking soda from the kitchen as an antacid to counteract acid reflux.

Share on PinterestAdd half a teaspoon of baking soda to a glass of water to relieve occasional heartburn.

Baking soda — or sodium bicarbonate — is a salt that consists of sodium ions and bicarbonate ions.

It usually appears as white crystalline solid or a fine powder. Tablets and capsules containing sodium bicarbonate are also available.

People mainly use baking soda as a rising agent, for example in cake making. It is also an ingredient in dental hygiene products and a natural cleaning agent.

For medical purposes, sodium bicarbonate can make the urine more alkaline, for example, if a person has a urinary tract infection. A doctor should supervise its use, however, as it can have adverse effects.

Baking soda has an alkaline pH, and it is a common remedy for the relief of heartburn and acid reflux. It neutralizes the excess stomach acid that causes symptoms.

The Canadian Society of Intestinal Research remind people that baking soda is a temporary solution to acid reflux. They advise people that sodium bicarbonate is available from a pharmacy in the form of tablets and effervescent powder.

However, they add: “If you are in a pinch, a half teaspoon of baking soda mixed in at least 125 milliliters (ml), or half a cup of water may provide a quick relief of symptoms.”

If you are using an OTC or prescription medication, follow the instructions on the package.

Doctors only recommend using baking soda temporarily, when symptoms first appear. This is because other problems may develop if the body becomes too alkaline. Baking soda is also a salt, and too much salt can lead to further problems.

As with other medications, it is essential to talk to a doctor about suitable dosages of sodium bicarbonate.

Children under 6 years old should only use sodium bicarbonate if a doctor prescribes it.

Acid reflux remedies containing baking soda are available for purchase online.

Common side effects of baking soda include:

  • gas and bloating
  • increased thirst
  • stomach cramps

If any of these symptoms persist or are severe, contact a doctor.

Anyone who experiences heartburn for longer than 2 weeks should also see a doctor.

Baking soda and existing medical conditions

People with the following medical conditions should avoid taking baking soda unless their doctor advises them to:

  • alkalosis, when the body’s pH is higher, or more alkali, than normal
  • appendicitis
  • edema, which is swelling caused by excess fluid in the body’s tissues
  • heart disease
  • high blood pressure
  • kidney disease
  • liver disease
  • preeclampsia, a condition during pregnancy that features high blood pressure, edema, and excess proteins in the urine

Baking soda is not suitable for acid reflux during pregnancy unless a doctor recommends it.

Sodium bicarbonate interactions

Baking soda can interfere with how the body absorbs some medications. People should not take it within 2 hours of other medicines.

It lowers stomach acid levels, which means it can interfere with the body’s ability to break down and absorb medications.

In addition, baking soda can interact with the following types of medications:

Share on PinterestMake sure you take baking soda with plenty of water, and check first with a doctor if you are taking another medication.

  • amphetamines, including dextroamphetamine and methamphetamine
  • benzphetamine
  • digoxin
  • elvitegravir
  • gefitinib
  • ketoconazole
  • ledipasvir
  • memantine
  • pazopanib

This list is not exhaustive, and sodium bicarbonate can interact with other medications.

People should always tell their doctor which medications they are taking, whether prescription, OTC, supplements, or alternative remedies when discussing the use of baking soda as an antacid.

There are many different treatments for acid reflux, including lifestyle changes, prescription and OTC medications, and surgical interventions.

Lifestyle changes

People can reduce heartburn and acid reflux naturally by implementing some or all of the following changes:

Maintaining a healthy weight: Staying within a healthy weight range in relation to height can reduce some of the pressure on the stomach. This prevents the stomach acid from being forced up the food pipe.

Knowing and avoiding food triggers: Certain foods and drinks trigger acid reflux. Triggers vary between individuals, but they most commonly include alcohol, chocolate, garlic, onions, caffeine, fried foods, and high-fat foods. Avoiding triggers is a simple way to reduce heartburn.

Avoiding overeating or eating too quickly: Eating large meals makes it difficult for the lower esophageal sphincter (LES) to close properly. The LES acts as a valve that separates the food pipe from the stomach and stops acid from rising. Eating too quickly can also contribute to heartburn.

Sit up straight: Other eating habits that can reduce the risk of getting heartburn include sitting up straight to eat and waiting at least 2 to 3 hours after eating before lying down.

Wearing loose clothing: Tight-fitting clothing puts pressure on the stomach.

Quitting smoking: There is a clear link between smoking and GERD.

Raising the head of the bed: People who experience acid reflux at night may benefit from raising the head of their bed with blocks or wooden wedges.

Medications for acid reflux

If lifestyle changes do not help acid reflux, medication is usually the next treatment option. Some common prescription and OTC medications include:

Antacids: There are several antacids available other than baking soda for the relief of acid reflux and heartburn. A doctor or pharmacist can advise on the different options.

H-2-receptor blockers: These medications lower acid production in the stomach for up to 12 hours. They are available from the pharmacy, with stronger versions available on prescription.

Proton pump inhibitors (PPIs): These medications are stronger than H-2-receptor blockers and block acid production for longer periods of time. This allows any damaged tissue in the food pipe time to heal. PPIs are available over the counter or on prescription.

Surgery for acid reflux and GERD

Medication is usually enough to treat GERD and acid reflux in most people.

If not, a doctor may recommend surgery.

Options include surgery to tighten the LES, or surgery to insert a magnetic device that prevents stomach acid from entering the LES.

When to see a doctor

People should talk to a doctor before taking baking soda for acid reflux.

Anyone who has an existing medical condition or is taking any medication should speak to a doctor before taking baking soda.

Without treatment, acid reflux can lead to more serious conditions and complications. If symptoms last for more than 2 weeks, the individual should contact their doctor.

Source: https://www.medicalnewstoday.com/articles/314932

Baking Soda Benefits: 11 Health And Beauty Benefits To Look Out For!

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

Sarika Rana  |  Updated: July 06, 2018 17:49 IST

You may agree; we all have a box of baking soda, which is barely used and is tucked in a corner of the kitchen shelf. This highly neglected humble kitchen ingredient is more than just adding fluff to your cakes and muffins. There are baking soda benefits that you may be unaware of. It is sodium bicarbonate that is not only used as a leavening agent in baked goods, but has super health and beauty benefits to look out for. An inexpensive purchase, baking soda is power-packed with antacid properties and is known to be a great alkalising agent. It is known to have many antiseptic properties along with being an amazing exfoliator. Baking soda is sodium bicarbonate that is generally used in baked goods. In its natural form, baking soda is known as nahcolite that is a part of the natural mineral natron. Natron contains large amounts of sodium bicarbonate, which has been used for quite some years now. It is believed that Egyptians used natron as soap for its cleansing properties. Soon after, people started manufacturing and selling the compound we know as baking soda.

(Also Read: 8 Surprising and Interesting Ways To Use Baking Soda)

Baking soda benefits: Baking soda is sodium bicarbonate that is generally used in baked goods

Apart from being used as a leavening agent, baking soda is also used as a natural deodorant, hand cleanser, toothpaste, teeth whitener, cleaner, et al.

While baking soda benefits are quite talked about, it is said that it should be consumed in small quantities as regular intake has been shown to support reduced general body functions by regulating the blood's natural pH levels, further reduced acid levels. This can hamper your complete body system functioning.

Baking soda soaked in water is one of the most ancient and highly effective remedies worldwide. Let us talk about baking soda benefits that will convince you to include this humble ingredient in some way or the other.

Baking soda benefits: Health benefits


1. Baking soda is a natural antacid

One of the baking soda benefits includes neutralising agent. Acid reflux is a common condition where stomach acid flows from the stomach back in to the oesophagus.

This process of acid may irritate your oesophagus and cause heart burn, a burning feeling that can occur anywhere between the abdomen and throat.

Sodium bicarbonate in baking soda neutralises the stomach acid and relieves the many symptoms of acid reflux and other stomach related issues.

Baking soda benefits: One of the baking soda benefits includes neutralising agent

2. Known to be a natural alkalising agent

It is known to be a natural alkalising agent. This non-toxic substance is used to reduce the effect of acid and inflammation in the body and treat most ailments. It is one of the best natural remedies for balancing the body's pH level and for improving overall health. Excess acid in the body can up the risk of osteoporosis, arthritis, et al.

3. Helps alleviate urinary tract infections

Baking soda and water solution is known to act as a protective barrier against urinary tract infections; it is due to its ability to reduce acid levels in urine. UTI, which is a very common condition that develops in women, this inexpensive remedy comes handy to you.

Baking Soda benefits: Baking soda and water solution is known to act as a protective barrier against UTI

4. It is known to be an exercise enhancer

The lactic acid released during physical activity or rigorous workouts has a tendency to accumulate in muscles and joints, creating stiffness and muscular fatigue. To prevent this from happening and affecting your physical performance, baking soda benefits come to your rescue. Drinking baking soda diluted in water can help control the condition.

5. Boosts kidney function

As an alkaline substance, baking soda reduces acid levels in the body and helps to keep the pH levels in check. According to a study published in the Journal of the American Society of Nephrology (JASN), the rate of decline in kidney function was greatly reduced – about two-thirds slower than in patients as compared to those who didn't take baking soda.

(Also Read: 8 Diet And Lifestyle Changes That Can Help Prevent Kidney Disease)

Baking soda benefits: baking soda reduces acid levels in the body

6. Treats gout and other joint problems

High levels of uric acid in the urine and blood in tissues throughout the body cause pain and chronic diseases arthritis and gout. Baking soda helps neutralise the excess acid and is used as an effective remedy.

Baking soda benefits: Beauty benefits


1. Makes for an amazing exfoliator

Baking soda is an excellent skin exfoliator; it is mildly abrasive in nature that helps remove the dead skin cells and allow new cell production, further giving a glow to the skin. All you need to do is to dilute baking soda in water and apply it on your face in a circular motion. Do not use this solution daily; instead, use it twice a week only.

(Also Read: 8 Ways To Use Baking Soda For Most Common Skin Problems)

Baking soda benefits: Baking soda is an excellent skin exfoliator

2. Prevents Acne

Baking soda reduces the inflammation on the skin and lowers the chances of developing acne and pimples. Its anti-bacterial properties help prevent breakouts on the skin.

3. Perfect for dark lips

Known as a popular cleansing agent, baking soda benefits dark lips too. All you need to do is to add honey and baking soda together and mix well. Apply it on your lips for two to three minutes before washing it off with water.

Baking soda benefits: Known as a popular cleansing agent, baking soda benefits dark lips too

4. Helps in teeth whitening

Baking soda is the most convenient toothpaste that helps give bright pearly whites. It helps remove the plaque on teeth, thanks to its abrasive nature. It may also help in removing discolouration due to the alkaline power it possesses.

5. A basic ingredient for hair care

While there is no scientific proof of baking soda being used as a perfect haircare solution, it is said that this ingredient helps soften your tresses and further promotes hair growth.

This magic kitchen ingredient deserves more attention that it actually gets. Make sure you bring these baking soda benefits to your rescue!


Source: https://food.ndtv.com/health/baking-soda-benefits-11-health-and-beauty-benefits-to-look-out-for-1834759

Sodium Bicarbonate (Baking Soda): Side Effects, Dosages, Treatment, Interactions, Warnings

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

Sodium bicarbonate is indicated in the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis.

Sodium bicarbonate is further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturate-protein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of hemoglobin and its breakdown products.

Sodium bicarbonate also is indicated in severe diarrhea, which is often accompanied by a significant loss of bicarbonate.

Treatment of metabolic acidosis should, if possible, be superimposed on measures designed to control the basic cause of the acidosis – e.g.

, insulin in uncomplicated diabetes, blood volume restoration in shock.

But since an appreciable time interval may elapse before all of the ancillary effects are brought about, bicarbonate therapy is indicated to minimize risks inherent to the acidosis itself.

Vigorous bicarbonate therapy is required in any form of metabolic acidosis where a rapid increase in plasma total CO2 content is crucial – e.g., cardiac arrest, circulatory insufficiency due to shock or severe dehydration, and in severe primary lactic acidosis or severe diabetic acidosis.

Dosages of Sodium Bicarbonate

Adult and Pediatric Dosage Forms and Strengths

Injectable solution


Dosage Considerations – Should be Given as Follows:

Cardiac Arrest

Adult, Initial: 1 mEq/kg/dose intravenous (IV) x1; base subsequent doses on results of arterial blood pH and PaCO2 as well as calculation of base deficit

Repeat doses may be considered in the setting of prolonged cardiac arrest only after adequate alveolar ventilation has been established

Infants, under 2 years (use 4.2% solution)

  • Initial: 1 mEq/kg/min given over 1-2 minutes intravenous/intraosseous (IV/IO), THEN
  • 1 mEq/kg IV q10min of arrest
  • Not to exceed 8 mEq/kg/day

Children over 2 years

  • Initial: 1 mEq/kg/dose intravenous (IV) x1; base subsequent doses on results of arterial blood pH and PaCO2 as well as calculation of base deficit
  • Repeat doses may be considered in the setting of prolonged cardiac arrest only after adequate alveolar ventilation has been established


  • 50 mEq intravenous (IV) over 5 minutes

Metabolic Acidosis (Non-Life-Threatening)

  • Adult: 2-5 mEq/kg intravenous (IV) infusion over 4-8 hours depending on the severity of acidosis as judged by the lowering of total CO2 content, clinical condition and pH
  • Older children: 2-5 mEq/kg IV infusion over 4-8 hours depending on the severity of acidosis as judged by the lowering of total CO2 content, clinical condition and pH

Severe Metabolic Acidosis (Except Hypercarbic Acidosis)

  • 90 to 180 mEq/L (~ 7.5-15 g) at a rate of 1-1.5 L (first hour); adjust for further management as neede


Source: https://www.rxlist.com/consumer_sodium_bicarbonate_baking_soda/drugs-condition.htm

Drugs & Medications

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects
Drugs & Medications

  • Uses
  • Side Effects
  • Precautions
  • Interactions
  • Overdose
  • Images
  • Uses
  • Side Effects
  • Precautions
  • Interactions
  • Overdose
  • Images


Sodium bicarbonate reduces stomach acid.

It is used as an antacid to treat heartburn, indigestion, and upset stomach. Sodium bicarbonate is a very quick-acting antacid. It should be used only for temporary relief. If you need to treat long-term stomach acid problems (such as peptic ulcer disease, GERD), talk with your doctor about other medications.

Sodium bicarbonate is the active ingredient in baking soda.

Take this medication by mouth, usually every 4 hours as needed or as directed by your doctor. Some tablets should be dissolved in a glass of water before swallowing. Other tablets may be swallowed whole or dissolved in water before swallowing. Follow all directions on the product package for the product you are taking. If you have any questions, ask your doctor or pharmacist.

If you are self-treating and your acid problems last or get worse after you have used this product for 2 weeks, or if you think you may have a serious medical problem, get medical help right away.

If you are using this medication regularly on a daily basis for more than 2 weeks, you may have a medical problem that needs different treatment. Ask your doctor if this is the right medication for you.

If your doctor has directed you to take this medication for acidosis or to alkalinize your urine, your dosage is your medical condition and response to treatment.

To get the most benefit from this medication, take it regularly, exactly as directed. It is usually taken by mouth several times a day. To help you remember, take it at the same times each day.

Do not increase the dose, take it more often, or continue taking this for longer than prescribed.

Side Effects

Nausea, bloating, or gas may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: swelling hands/ankles/feet, unusual weight gain.

When taken with sodium bicarbonate, large doses of calcium from your diet, medications, or supplements can rarely cause a serious problem called milk-alkali syndrome. Ask your doctor or pharmacist about using calcium products safely while you are using this medication.

Tell your doctor right away if you have any serious side effects, including: dizziness, muscle aches/spasms, mental/mood changes (such as confusion, irritability, memory problems), vomiting, weakness, signs of kidney problems (such as change in the amount of urine).

Get medical help right away if you have any very serious side effects, including: chest pain, seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US –

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Source: https://www.webmd.com/drugs/2/drug-11325/sodium-bicarbonate-oral/details

Sodium Bicarbonate: Health Benefits, Uses, Side Effects, Dosage & Interactions

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

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Source: https://www.rxlist.com/sodium_bicarbonate/supplements.htm

Sodium bicarbonate Side Effects: Common, Severe, Long Term – Drugs.com

10 Uses of Sodium Bicarbonate (Baking Soda) + Side Effects

Applies to sodium bicarbonate: granule, solution, tablet

Along with its needed effects, sodium bicarbonate may cause some unwanted effects. Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more ly to occur if it is taken: in large doses, for a long time, or by patients with kidney disease.

Check with your doctor as soon as possible if any of the following side effects occur while taking sodium bicarbonate:

  • Frequent urge to urinate
  • headache (continuing)
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • nausea or vomiting
  • nervousness or restlessness
  • slow breathing
  • swelling of feet or lower legs
  • unpleasant taste
  • unusual tiredness or weakness

Some side effects of sodium bicarbonate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Increased thirst
  • stomach cramps

For Healthcare Professionals

Applies to sodium bicarbonate: compounding powder, intravenous solution, oral tablet


Chronic ingestion of bicarbonate may rarely cause intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia. In this rare circumstance, the serum potassium may be elevated.

Rare cases of sodium bicarbonate abuse have been associated with features of Munchausen syndrome. These patients often present with an otherwise unexplained hypokalemic hypochloremic metabolic alkalosis.

Hypernatremia may cause water retention, weight gain, and edema, which may be important in some patients with congestive heart failure, renal insufficiency, or severe liver disease.[Ref]

Metabolic side effects have included metabolic alkalosis, hypernatremia/hyperosmolarity, hypochloremia, and hypokalemia. These effects have been associated with rapid or prolonged administration. Side effects have rarely included intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia.[Ref]


The respiratory drive may be suppressed after bicarbonate administration due to increased venous C02 concentration. Without adequate ventilation, worsened systemic acidosis could develop.[Ref]

Respiratory side effects have included suppressed respiratory drive.[Ref]

Nervous system

Rapid infusion of hyperosmolar sodium bicarbonate has been associated with intraventricular hemorrhage in the pediatric literature.

Irritability and tetany have been associated with sodium bicarbonate-induced alkalosis or hypernatremia.

Due to greater permeability of the blood-brain barrier to hydrogen than to bicarbonate, the pH of cerebrospinal fluid may significantly decrease during sodium bicarbonate administration, which can cause mental stupor or coma.[Ref]

Nervous system side effects have included irritability, tetany, mental stupor, coma, and intraventricular hemorrhage.[Ref]


Local side effects have included IV site pain, venous irritation, and extravasation. Cellulitis, tissue necrosis, ulceration, or skin sloughing have possibly been the result of extravasation. A slow rate of administration of a properly diluted solution into a large bore needle and vein is recommended if IV administration is necessary.[Ref]


Cardiovascular side effects have included decreased cardiac contractility possibly resulting from infusion of sodium bicarbonate in patients with severe acidosis.[Ref]

Experimentally, the administration of intravenous hypertonic sodium bicarbonate has been associated with increased serum osmolality, decreased ionized serum calcium (which is associated with decreased myocardial contractility), and peripheral vasodilation. Some experts recommend invasive hemodynamic monitoring in acidotic patients before the administration of bicarbonate.[Ref]


Gastrointestinal side effects associated with oral administration have rarely included gastric rupture.[Ref]

As an antacid, sodium bicarbonate, especially after excess food or liquid, can cause excess gas release (when combined with gastric acid). The mortality associated with gastric rupture is as high as 65%.[Ref]


Urinary alkalinization from bicarbonate can cause a falsely positive colorimetric assay for protein.[Ref]

Renal side effects have rarely included “False proteinuria”.[Ref]

1. Wu DJ, Mifune J, Taga K, Hifumi S, Takahashi Y, Yamashida S, Nishioka S, Murakami T, Tanaka T “Anginal attack following a sodium bicarbonate and hydrocortisone injection.” Jpn Heart J 31 (1990): 109-13

2. “Product Information. Sodium Bicarbonate (sodium bicarbonate).” Astra USA, Westborough, MA.

3. Cooper DJ, Walley KR, Wiggs BR, Russell JA “Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosisis.” Ann Intern Med 112 (1990): 492-8

4. Arieff AI “Managing metabolic acidosis: update on the sodium bicarbonate controversy.” J Crit Illn 8 (1993): 224-46

5. Oster JR, Perez GO, Rosen MS “Hyporeninemic hypoaldosteronism after chronic sodium bicarbonate abuse.” Arch Intern Med 136 (1976): 1179-80

6. Hazard PB, Griffin JP “Sodium bicarbonate in the management of systemic acidosis.” South Med J 73 (1980): 1339-42,1348

7. Kennedy S “Sodium bicarbonate abuse in anorexia nervosa.” J Clin Psychiatry 49 (1988): 168

8. Linford SM, James HD “Sodium bicarbonate abuse: a case report.” Br J Psychiatry 149 (1986): 502-3

9. Thomas SH, Stone CK “Acute toxicity from baking soda ingestion.” Am J Emerg Med 12 (1994): 57-9

10. Okada H, Inoue T, Takahira S, Sugahara S, Nakamoto H, Suzuki H “Daytime hypertension, sleep apnea and metabolic alkalosis in a haemodialysis patient – the result of sodium bicarbonate abuse.” Nephrol Dialysis Transplant 14 (1999): 452-4

11. Griffith J, White P “Acute asthma precipitated by accidental inhalation of sodium bicarbonate granules (Carbex).” Clin Radiol 49 (1994): 435

12. Lou HC, Lassen NA, Fris-Hansen B “Decreased cerebral blood flow after administration of sodium bicarbonate in the distressed newborn infant.” Acta Neurol Scand 57 (1978): 239-47

13. Papile LA, Burstein J, Burstein R, Koffler H, Koops B “Relationship of intravenous sodium bicarbonate infusions and cerebral intraventricular hemorrhage.” J Pediatr 93 (1978): 834-6

14. Speer ME, Rudolph AJ “Calcification of superficial scalp veins secondary to intravenous infusion of sodium bicarbonate and calcium chloride.” Cutis 32 (1983): 65-6

15. Prakash P, Saxena S “Complication of sodium bicarbonate therapy–a case report.” Indian J Pediatr 45 (1978): 277-8

16. Bleske BE, Warren EW, Rice TL, Gilligan LJ, Tait AR “Effect of high-dose sodium bicarbonate on the vasopressor effects of epinephrine during cardiopulmonary resuscitation.” Pharmacotherapy 15 (1995): 660-4

17. Cooper DJ, Worthley LI “Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis.” Intensive Care Med 13 (1987): 425-7

18. Rao RS, Graver ML, Urivetsky M, Scharf SM “Mechanisms of myocardial depression after bolus injection of sodium bicarbonate.” J Crit Care 9 (1994): 255-61

19. Fordtran JS, Morawski SG, Santa Ana CA, Rector FC, Jr “Gas production after reaction of sodium bicarbonate and hydrochloric acid.” Gastroenterology 87 (1984): 1014-21

20. Mastrangelo MR, Moore EW “Spontaneous rupture of the stomach in a healthy adult man after sodium bicarbonate ingestion.” Ann Intern Med 101 (1984): 649-50

21. Brismar B, Strandberg A, Wiklund B “Stomach rupture following ingestion of sodium bicarbonate.” Acta Chir Scand Suppl 530 (1986): 97-9

22. Downs NM, Stonebridge PA “Gastric rupture due to excessive sodium bicarbonate ingestion.” Scott Med J 34 (1989): 534-5

23. Lazebnik N, Iellin A, Michowitz M “Spontaneous rupture of the normal stomach after sodium bicarbonate ingestion.” J Clin Gastroenterol 8 (1986): 454-6

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer

Source: https://www.drugs.com/sfx/sodium-bicarbonate-side-effects.html